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KMID : 0948920130120020095
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Clinical Pain
2013 Volume.12 No. 2 p.95 ~ p.98
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Acute Metabolic Encephalopathy Induced by Low Dose Baclofen Treatment for Complex Regional Pain Syndrome
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Jung Kang-Jae
Park Ji-Young
Hwang Do-Won
Kim Jae-Hyung
Park Yoon-Ghil
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Abstract
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Baclofen can induce significant neurologic side effects. We report a case of acute Baclofen induced encephalopathy in a 44-year old female patient. She was diagnosed with chronic kidney disease due to focal segmental glomer-ulonephritis and has been received peritoneal dialysis for 1 year. She had a acute basal ganglia hemorrhage in the right cerebral hemisphere and then received surgical management. After 1 months after the onset of hemor-rhage, she has developed pain, swelling and paresthesia of the left upper extremity. She was diagnosed with com-plex regional pain syndrome. Medications were limited be-cause of the possibility of renal intoxication. She was pre-scribed Baclofen 5 mg, additionally. After then she pro-gressively showed confused mental status and dysarthria and was diagnosed with acute metabolic encephalopathy. We started intensive hemodialysis and gradually she showed improvement in mental status and dysarthria. After 6 day treatment, she had fully recovery.
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KEYWORD
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Baclofen, Complex regional pain syndrome, Ence-phalopathy
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